Description

Thieno[3,4-B]-1,4-Dioxin, 2,3-Dihydro-5,7-Bis(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl) is a high-purity, advanced organic building block featuring two pinacol boronate ester groups, making it a versatile intermediate for complex molecular synthesis. This compound matters for its critical role in facilitating Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology in modern pharmaceutical and materials science research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and organic electronics industries for constructing novel conjugated systems and heterocyclic frameworks.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in creating complex heterocyclic cores for oncology and CNS therapeutics.
• Organic Electronic Materials: Precursor for conjugated polymers and small molecules used in Organic Light-Emitting Diodes (OLEDs), Organic Photovoltaics (OPVs), and Field-Effect Transistors (OFETs).
• Agrochemical Synthesis: Used in developing advanced active ingredients with complex aromatic and heteroaromatic structures.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and catalysts used in asymmetric synthesis and other catalytic processes.
• Polymer Chemistry: Enables the synthesis of functionalized polymers with tailored electronic or optical properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological systems.

Basic Information

Product Name	Thieno[3,4-B]-1,4-Dioxin, 2,3-Dihydro-5,7-Bis(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)
CAS No.	1426818-50-9
Molecular Formula	C₂₂H₃₂B₂O₆S
Molecular Weight	438.08 g/mol
Synonyms	5,7-Bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2,3-dihydrothieno[3,4-b][1,4]dioxine; 2,3-Dihydrothieno[3,4-b][1,4]dioxine-5,7-diylbis(4,4,5,5-tetramethyl-1,3,2-dioxaborolane); Thieno[3,4-b]-1,4-dioxin-5,7-diboronic acid bis(pinacol) ester; 1426818-50-9; AKOS040759246; BRN 19125938
EINECS	Contact for details

Quality Control

Every batch of our Thieno[3,4-B]-1,4-Dioxin, 2,3-Dihydro-5,7-Bis(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl) undergoes rigorous analytical testing to ensure high purity and batch-to-batch consistency, meeting the stringent requirements of research and process chemistry. Our quality protocols are designed to support cGMP-compliant development. Comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., argon or nitrogen) due to its moisture-sensitive nature. Allow the sealed container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.