Description

4-Fluoro-1,4'-Bipiperidine Hydrochloride is a high-purity, advanced pharmaceutical intermediate and research chemical. This compound is valued for its role as a key building block in the synthesis of complex molecules, particularly in medicinal chemistry. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly those targeting the central nervous system.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic agents.
• Organic Synthesis: Serves as a versatile precursor for introducing the fluorinated bipiperidine moiety into more complex molecular architectures.
• Chemical Reference Standard: Employed as a high-purity standard for analytical method development and quality control in API manufacturing.
• Biochemical Tool Compound: Utilized in biochemical assays and pharmacological research to study specific biological pathways and receptor interactions.

Basic Information

Product Name	4-Fluoro-1,4'-Bipiperidine Hydrochloride
CAS No.	1426290-04-1
Molecular Formula	C10H19FN2•HCl
Molecular Weight	222.73 g/mol (Free base: 186.27 g/mol)
Synonyms	1,4'-Bipiperidine, 4-fluoro-, hydrochloride; 4-Fluoro-1,4'-bipiperidine HCl; 4-Fluorobipiperidine hydrochloride; 1-(4-Fluoropiperidin-1-yl)piperidine hydrochloride; 4-Fluoro-1,4'-bipiperidinium chloride; 4-Fluoro-1,1'-bipiperidine hydrochloride; 4-Fluorobipiperidine HCl salt
EINECS	Contact for details

Quality Control

Our 4-Fluoro-1,4'-Bipiperidine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing results from HPLC, NMR, and other relevant tests to meet the stringent requirements of pharmaceutical R&D and production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.