Description

tert-Butyl 4-((4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Methylene)Piperidine-1-Carboxylate is a high-value, protected piperidine boronic ester building block designed for advanced organic synthesis. This compound is critical for enabling efficient cross-coupling reactions, particularly Suzuki-Miyaura couplings, to construct complex molecular architectures. It is an essential intermediate for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries seeking to develop new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, oncology, and infectious diseases.
• Suzuki-Miyaura Cross-Coupling Reagent: Enables the formation of carbon-carbon bonds to introduce the functionalized piperidine moiety into complex molecules under mild conditions.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides requiring specific heterocyclic scaffolds.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands or metal-organic frameworks (MOFs) with tailored properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and protein function.
• Material Science Research: A precursor for organic electronic materials, such as those used in OLEDs or conductive polymers, where the piperidine structure modulates electronic properties.

Basic Information

Product Name	tert-Butyl 4-((4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Methylene)Piperidine-1-Carboxylate
CAS No.	1425970-61-1
Molecular Formula	C17H30BNO4
Molecular Weight	323.24 g/mol
Synonyms	1-Boc-4-((4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)methylene)piperidine; 1-(tert-Butoxycarbonyl)-4-[(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)methylidene]piperidine; 4-((4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)methylene)piperidine-1-carboxylic acid tert-butyl ester; tert-Butyl 4-((4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)methylene)-1-piperidinecarboxylate; BOC-Piperidine-4-boronic acid pinacol ester; 1-Boc-4-methylene-piperidine-4-boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Every batch of tert-Butyl 4-((4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Methylene)Piperidine-1-Carboxylate is manufactured and tested under strict quality management systems to ensure consistency and reliability for your critical research and development. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to verify identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.