Description

4-Bromo-2-(Methylsulfonyl)-1-Nitrobenzene is a high-purity, multi-functional aromatic building block designed for advanced chemical synthesis. This compound matters for its unique combination of reactive bromo, nitro, and methylsulfonyl groups, enabling precise molecular construction in complex organic frameworks. It is primarily needed by researchers and process chemists in the pharmaceutical, agrochemical, and specialty materials industries for developing novel active ingredients and functional intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting specific enzyme inhibitors or receptor modulators.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, leveraging its halogen and sulfone functionalities.
• Material Science Research: Serves as a building block for creating specialized polymers, liquid crystals, or organic electronic materials.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Heck, or Buchwald-Hartwig amination.
• Nucleophilic Aromatic Substitution: The activated nitro and sulfone groups facilitate substitution reactions for introducing diverse functional groups.
• Chemical Reference Standard: Used in analytical laboratories for method development, calibration, and quality control of related compounds.

Basic Information

Product Name	4-Bromo-2-(Methylsulfonyl)-1-Nitrobenzene
CAS No.	1423033-81-1
Molecular Formula	C7H6BrNO4S
Molecular Weight	280.10 g/mol
Synonyms	1-Bromo-4-(methylsulfonyl)-2-nitrobenzene; 4-Bromo-2-methylsulfonyl-1-nitrobenzene; 2-Methylsulfonyl-4-bromo-1-nitrobenzene; 1-Nitro-4-bromo-2-(methylsulfonyl)benzene; Benzene, 1-bromo-4-(methylsulfonyl)-2-nitro-; 4-Bromo-1-nitro-2-(methylsulfonyl)benzene
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-(Methylsulfonyl)-1-Nitrobenzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our commitment to quality supports compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be opaque or stored in a dark environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.