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(3-Methoxy-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Methanol CAS NO 1422655-38-6


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CAS No.:1422655-38-6

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

(3-Methoxy-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Methanol is a high-value boronic ester derivative, a crucial building block in modern synthetic organic chemistry. This compound matters because it serves as a protected boronic acid, offering enhanced stability and solubility for critical cross-coupling reactions like the Suzuki-Miyaura reaction. Pharmaceutical, agrochemical, and advanced materials researchers need it for the efficient synthesis of complex molecules, enabling the development of new active ingredients and functional polymers.

Application

  • Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) via palladium-catalyzed cross-coupling reactions.
  • Agrochemical Synthesis: Used in constructing novel herbicide and fungicide molecules with specific biological activity.
  • Material Science: Serves as a monomer or functionalization agent in the production of organic electronic materials, such as OLEDs and conductive polymers.
  • Chemical Biology & Proteomics: Employed as a bioconjugation reagent or in the development of enzyme inhibitors and molecular probes.
  • Ligand Synthesis: Acts as a building block for creating sophisticated chiral and achiral ligands used in catalysis.
  • Academic & Industrial R&D: Essential for medicinal chemistry programs and process development in research laboratories worldwide.

Basic Information

Product Name (3-Methoxy-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Methanol
CAS No. 1422655-38-6
Molecular Formula C14H21BO4
Molecular Weight 264.13 g/mol
Synonyms 2-(4-(Hydroxymethyl)-2-methoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; (4-(Hydroxymethyl)-2-methoxyphenyl)boronic acid pinacol ester; 4-(Hydroxymethyl)-2-methoxyphenylboronic acid pinacol ester; 3-Methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenemethanol; Pinacol [4-(hydroxymethyl)-2-methoxyphenyl]boronate; CAS 1422655-38-6
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Quality Control

Our (3-Methoxy-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Methanol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with REACH and other relevant global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to maintain stability and prevent decomposition.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Assay (HPLC) ≥97.0%
Purity (HPLC, Area%) ≥98.0%
Water Content (KF) ≤0.5%
Residue on Ignition ≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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