Description

2-[4-(Bromomethyl)Naphthalen-1-Yl]-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-value naphthalene-based boronic ester derivative, serving as a critical building block in modern synthetic chemistry. Its core value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone of pharmaceutical and advanced materials development. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and organic electronics industries who require reliable, high-purity intermediates for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing naphthalene scaffolds.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides with tailored properties.
• Organic Light-Emitting Diodes (OLEDs): Building block for constructing sophisticated organic semiconductors and charge-transport materials.
• Polymer Chemistry: Monomer for synthesizing specialty polymers with specific optical or electronic functionalities.
• Ligand and Catalyst Development: Intermediate for creating novel ligands and organometallic catalysts used in asymmetric synthesis.
• Material Science Research: Used in the development of metal-organic frameworks (MOFs) and other advanced porous materials.
• Chemical Biology Probes: Serves as a handle for bioconjugation and the development of molecular probes and sensors.

Basic Information

Product Name	2-[4-(Bromomethyl)Naphthalen-1-Yl]-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	1422655-33-1
Molecular Formula	C₁₇H₂₀BBrO₂
Molecular Weight	347.06 g/mol
Synonyms	1-(Bromomethyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)naphthalene; 4-(Bromomethyl)-1-naphthaleneboronic acid pinacol ester; (4-(Bromomethyl)naphthalen-1-yl)boronic acid pinacol ester; 2-(4-(Bromomethyl)-1-naphthyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; PINACOL (4-(BROMOMETHYL)-1-NAPHTHYL)BORONATE; 1-Naphthaleneboronic acid, 4-(bromomethyl)-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our 2-[4-(Bromomethyl)Naphthalen-1-Yl]-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, meeting the stringent requirements of research and process chemistry. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards and can provide material tailored to specific project needs, including custom purity grades.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.