Description

n-Ethyl-3-Nitro-5-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-2-Amine is a high-value, functionalized pyridine derivative containing a pinacol boronate ester group. This compound serves as a critical advanced pharmaceutical intermediate (API) and versatile building block in modern synthetic chemistry. It is primarily utilized by R&D and production teams in the pharmaceutical, agrochemical, and materials science industries for constructing complex molecular architectures.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: As a key boronic ester reagent for forming carbon-carbon bonds in the synthesis of complex organic molecules.
• Pharmaceutical Intermediate: For the research and development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and other small-molecule drug candidates.
• Agrochemical Synthesis: As a building block in the creation of new herbicides, fungicides, and insecticides with enhanced efficacy.
• Ligand and Catalyst Development: In the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Materials Science Research: For the synthesis of organic electronic materials, such as those used in OLEDs and semiconductors.
• Chemical Biology Probes: In the design and synthesis of molecular probes for studying biological pathways and protein interactions.

Basic Information

Product Name	n-Ethyl-3-Nitro-5-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-2-Amine
CAS No.	1421854-75-2
Molecular Formula	C13H20BN3O4
Molecular Weight	293.13 g/mol
Synonyms	2-Amino-6-ethyl-5-nitropyridine-3-boronic acid pinacol ester; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3-nitro-2-(ethylamino)pyridine; 2-(Ethylamino)-3-nitro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 3-Nitro-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)-N-ethylpyridin-2-amine; PINACOL (3-NITRO-5-(ETHYLAMINO)PYRIDIN-2-YL)BORONATE; (3-Nitro-5-((ethylamino)pyridin-2-yl)boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our production of n-Ethyl-3-Nitro-5-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-2-Amine adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.