Description

cis-Ethyl 2-(Boc-Amino)Cyclopropanecarboxylate is a high-purity, protected amino acid derivative featuring a cyclopropane ring, a key structural motif in medicinal chemistry. This compound serves as a versatile and critical chiral building block for the synthesis of complex bioactive molecules. It is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for constructing novel drug candidates and active ingredients. The ethyl ester and tert-butoxycarbonyl (Boc) protecting group offer excellent stability and reactivity for selective synthetic transformations.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of protease inhibitors, antiviral agents, and other small-molecule therapeutics.
• Peptidomimetics Research: Used to incorporate constrained, non-natural amino acid residues into peptide backbones to enhance metabolic stability and biological activity.
• Agrochemical Synthesis: Serves as a building block for developing novel pesticides and herbicides with unique modes of action.
• Chemical Biology Probes: Employed in the creation of labeled or tagged compounds for studying enzyme mechanisms and biological pathways.
• Methodology Development: Used in academic and industrial research to develop new asymmetric synthesis and ring-opening reactions.
• Custom Synthesis & Contract Manufacturing: A starting material for the custom production of advanced intermediates under cGMP or research-grade conditions.

Basic Information

Product Name	cis-Ethyl 2-(Boc-Amino)Cyclopropanecarboxylate
CAS No.	1421676-91-6
Molecular Formula	C11H19NO4
Molecular Weight	229.27 g/mol
Synonyms	Ethyl (1R,2S)-2-[(tert-Butoxycarbonyl)amino]cyclopropanecarboxylate; (1R,2S)-Ethyl 2-((tert-butoxycarbonyl)amino)cyclopropanecarboxylate; cis-2-((tert-Butoxycarbonyl)amino)cyclopropanecarboxylic Acid Ethyl Ester; Boc-ACPC-OEt; (1R,2S)-Boc-ACPC-OEt; Boc-(1R,2S)-2-Aminocyclopropanecarboxylic Acid Ethyl Ester; Ethyl cis-2-(Boc-amino)cyclopropanecarboxylate; N-Boc-cis-2-Aminocyclopropanecarboxylic Acid Ethyl Ester
EINECS	Contact for details

Quality Control

Our cis-Ethyl 2-(Boc-Amino)Cyclopropanecarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure compliance with research and development standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent decomposition. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% de
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.