Description

Methyl 2-Hydroxy-3-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzoate is a high-value, synthetically versatile organoboron building block. This compound matters for its role as a key intermediate in modern cross-coupling reactions, enabling the precise construction of complex molecular architectures. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for synthesizing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A crucial precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing biaryl and heterobiaryl scaffolds found in active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific boronic ester functionalities.
• Material Science Research: Serves as a building block for creating organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Chemical Biology & Probe Development: Employed in the synthesis of molecular probes and tags for bio-conjugation and imaging applications.
• Academic & Contract Research: A valuable reagent for methodology development and complex molecule synthesis in academic and industrial research laboratories.
• Custom Synthesis: Acts as a starting material for contract manufacturing organizations (CMOs) producing specialized fine chemicals for client projects.

Basic Information

Product Name	Methyl 2-Hydroxy-3-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzoate
CAS No.	1421322-59-9
Molecular Formula	C14H19BO5
Molecular Weight	278.11 g/mol
Synonyms	2-Hydroxy-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoic acid methyl ester; Methyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)salicylate; 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)salicylic acid methyl ester; Methyl 2-hydroxy-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate; Pinacol ester of Methyl 2-hydroxy-3-boronobenzoate; 3-Borono-2-hydroxybenzoic acid methyl ester pinacol ester
EINECS	Contact for details

Quality Control

Our Methyl 2-Hydroxy-3-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzoate is produced under strict quality management systems to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot undergoes rigorous analytical testing, including HPLC, NMR (1H, 13C, 11B), and GC/MS, to verify identity, purity, and the absence of critical impurities. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis and maintain product integrity. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.