Description

2-Methyl-6-(Methylthio)-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine is a high-value, multi-functional organoboron building block essential for modern synthetic chemistry. This compound matters because it enables efficient, precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone of pharmaceutical and advanced materials development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and organic electronics industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used to create novel herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Material Science Research: Serves as a monomer or functionalization agent in the development of organic semiconductors, OLED materials, and conductive polymers.
• Chemical Biology & Medicinal Chemistry: Employed in the discovery and optimization of drug candidates through structure-activity relationship (SAR) studies and library synthesis.
• Cross-Coupling Reactions: Specifically designed as a versatile boronic ester pinacol ester for palladium-catalyzed Suzuki-Miyaura couplings with various aryl/heteroaryl halides.
• Custom Synthesis & Contract Manufacturing: A critical raw material for CROs and CDMOs producing bespoke compounds for client projects.

Basic Information

Product Name	2-Methyl-6-(Methylthio)-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine
CAS No.	1420296-82-7
Molecular Formula	C14H22BNO2S
Molecular Weight	279.21 g/mol
Synonyms	3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-methyl-6-(methylthio)pyridine; 2-Methyl-6-(methylthio)pyridine-3-boronic acid pinacol ester; 6-(Methylthio)-2-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; Pinacol [2-methyl-6-(methylthio)pyridin-3-yl]boronate; Boronic acid, B-[2-methyl-6-(methylthio)-3-pyridinyl]-, 1,1-dimethylethyl ester; 2-Methyl-6-methylthio-3-pyridineboronic acid pinacol ester; CAS 1420296-82-7
EINECS	Contact for details

Quality Control

Every batch of 2-Methyl-6-(Methylthio)-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure consistency and purity. Our standard quality commitment includes comprehensive analysis via HPLC, NMR (1H, 13C, 11B), and GC/MS to confirm identity and assay. Certificates of Analysis (COA) detailing all specifications are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) in a desiccator for long-term storage. Optimal storage temperature is 2-8°C for extended stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (GC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.