Description

tert-Butyl Spiro[2.3]Hexane-5-Ylcarbamate is a specialized organic compound featuring a unique spirocyclic structure. This high-purity intermediate is critical for the synthesis of complex pharmaceutical molecules, offering a versatile building block for medicinal chemistry research and development. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries seeking to introduce novel three-dimensional frameworks into their target compounds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those requiring spirocyclic motifs for enhanced biological activity or pharmacokinetic properties.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to explore new chemical space and develop novel therapeutic agents.
• Agrochemical Synthesis: Serves as a precursor in the development of advanced crop protection agents and pesticides with novel modes of action.
• Chemical Biology Probes: Employed in the creation of specialized molecular probes for studying biological pathways and target engagement.
• Process Chemistry Development: Utilized in scaling up synthetic routes from laboratory to pilot plant scale for commercial production.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for fine chemical manufacturers offering bespoke synthesis services to the life sciences sector.

Basic Information

Product Name	tert-Butyl Spiro[2.3]Hexane-5-Ylcarbamate
CAS No.	1420270-95-6
Molecular Formula	C11H19NO2
Molecular Weight	197.27 g/mol
Synonyms	5-(((tert-Butoxy)carbonyl)amino)spiro[2.3]hexane; tert-Butyl N-(spiro[2.3]hexan-5-yl)carbamate; Spiro[2.3]hexane-5-carbamic acid, 1,1-dimethylethyl ester; Boc-Spiro[2.3]hexane-5-amine; 5-(Boc-amino)spiro[2.3]hexane; tert-Butyl (spiro[2.3]hexan-5-yl)carbamate; 1420270-95-6
EINECS	Contact for details

Quality Control

Our tert-Butyl Spiro[2.3]Hexane-5-Ylcarbamate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for advanced synthetic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support development and commercial projects requiring material that meets ICH Q3A/B guidelines for impurities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.