Description

2-Oxa-6-Azaspiro[3.3]Heptane is a versatile and structurally unique spirocyclic building block of significant interest in advanced organic synthesis. Its rigid, three-dimensional scaffold is highly valued for constructing complex molecular architectures with improved pharmacological properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: A key synthon for developing novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral drug discovery programs.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides and insecticides, leveraging its spirocyclic structure for enhanced bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chelating ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of specialty polymers and advanced organic frameworks (e.g., MOFs, COFs) due to its conformational rigidity.
• Chemical Biology Probe: Utilized as a core structure in designing molecular probes and tools for studying biological systems and enzyme inhibition.

Basic Information

Product Name	2-Oxa-6-Azaspiro[3.3]Heptane
CAS No.	174-78-7
Molecular Formula	C5H9NO
Molecular Weight	99.13 g/mol
Synonyms	2-Oxa-6-azaspiro[3.3]heptane; 6-Oxa-2-azaspiro[3.3]heptane; 1-Oxa-4-azaspiro[2.3]hexane; Spiro[2.3]hexane, 1-oxa-4-aza-; 2,6-Dioxa-4-azaspiro[3.3]heptane (tautomer); Azaspiroheptane oxide; 1,4-Oxazaspiro[2.3]hexane; AOSPH
EINECS	Contact for details

Quality Control

Our 2-Oxa-6-Azaspiro[3.3]Heptane is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chromatography (HPLC, GC) and spectroscopic methods (NMR, IR), to ensure high chemical purity and identity. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.