Description

4-Chloro-4-Methyl-2-(Trifluoromethyl)-1,1-Biphenyl is a high-value, multi-functional biphenyl derivative characterized by its unique trifluoromethyl and chloro substituents. This compound serves as a critical advanced pharmaceutical intermediate (API) and a versatile building block in modern organic synthesis. It is essential for research and production in the pharmaceutical, agrochemical, and advanced materials sectors, where its specific halogenated and fluorinated structure enables the development of novel active compounds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, anti-inflammatory agents, and antiviral drugs.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a core structural unit in the production of specialty chemicals for electronic displays and organic light-emitting diodes (OLEDs).
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Stille) and as a precursor for more complex fluorinated aromatic systems in academic and industrial R&D.
• Material Science Research: Investigated for use in polymers and advanced coatings to impart specific chemical resistance and thermal stability properties.

Basic Information

Product Name	4-Chloro-4-Methyl-2-(Trifluoromethyl)-1,1-Biphenyl
CAS No.	1419798-91-6
Molecular Formula	C14H10ClF3
Molecular Weight	270.68 g/mol
Synonyms	4'-Chloro-4-methyl-2'-(trifluoromethyl)-1,1'-biphenyl; 4-Methyl-4'-chloro-2'-(trifluoromethyl)biphenyl; 2-(Trifluoromethyl)-4-chloro-4'-methylbiphenyl; [1,1'-Biphenyl]-4-carbonitrile, 4'-chloro-2'-(trifluoromethyl)-; Biphenyl, 4-chloro-4-methyl-2-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 4-Chloro-4-Methyl-2-(Trifluoromethyl)-1,1-Biphenyl is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.