Description

Boronic Acid, B-[4-(Difluoromethyl)-3,5-Difluorophenyl]- is a highly functionalized organoboron compound characterized by its unique difluoromethyl and difluorophenyl substituents. This compound is a critical advanced pharmaceutical intermediate (API) and a versatile building block in modern synthetic chemistry, enabling the formation of carbon-carbon bonds via Suzuki-Miyaura cross-coupling reactions. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system (CNS) disorders, oncology, and metabolic diseases.
• Suzuki-Miyaura Cross-Coupling Reagent: Essential for constructing complex biaryl and heterobiaryl structures in medicinal chemistry and material science research.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and insecticides with enhanced efficacy and environmental profiles.
• Ligand for Catalysis: Can be employed in the development of novel organometallic catalysts and ligands for asymmetric synthesis.
• Material Science Building Block: Incorporated into organic electronic materials, such as OLEDs and OFETs, to modify electronic properties and stability.
• Chemical Biology Probe: Utilized in the design of activity-based probes and sensors for studying biological processes.

Basic Information

Product Name	Boronic Acid, B-[4-(Difluoromethyl)-3,5-Difluorophenyl]-
CAS No.	1418595-79-5
Molecular Formula	C8H5BF4O2
Molecular Weight	219.93 g/mol
Synonyms	[4-(Difluoromethyl)-3,5-difluorophenyl]boronic acid; (4-(Difluoromethyl)-3,5-difluorophenyl)boronic acid; 4-(Difluoromethyl)-3,5-difluorobenzeneboronic acid; B-[4-(Difluoromethyl)-3,5-difluorophenyl]boronic acid; 1418595-79-5; Boronic acid, B-[4-(difluoromethyl)-3,5-difluorophenyl]-; 3,5-Difluoro-4-(difluoromethyl)phenylboronic acid
EINECS	Contact for details

Quality Control

Our Boronic Acid, B-[4-(Difluoromethyl)-3,5-Difluorophenyl]- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency suitable for demanding research and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when prolonged exposure is anticipated to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.