Description

1-(3-Bromo-4-(Hydroxymethyl)Phenyl)Ethanone is a specialized brominated aromatic ketone building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both a reactive acetyl group and a hydroxymethyl substituent on a brominated benzene ring, makes it a versatile precursor for constructing complex molecules. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, inflammation, and oncology.
• Agrochemical Research: Serves as a foundational building block for developing new herbicides, fungicides, and plant growth regulators with enhanced efficacy.
• Liquid Crystal & OLED Material Precursor: Used in the research and development of advanced electronic materials, including liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs).
• Polymer Modification Agent: Employed to introduce functional bromo and hydroxyl groups into polymer backbones, altering physical and chemical properties for specialty applications.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Sonogashira) to create complex biaryl and conjugated systems.
• Chemical Biology Probe Synthesis: Utilized in the design and synthesis of molecular probes and tags for studying biological processes and protein interactions.

Basic Information

Product Name	1-(3-Bromo-4-(Hydroxymethyl)Phenyl)Ethanone
CAS No.	1418144-62-3
Molecular Formula	C9H9BrO2
Molecular Weight	229.07 g/mol
Synonyms	3'-Bromo-4'-(hydroxymethyl)acetophenone; 1-(3-Bromo-4-(hydroxymethyl)phenyl)ethan-1-one; 3-Bromo-4-(hydroxymethyl)acetophenone; 4-Acetyl-2-bromobenzyl alcohol; 2-Bromo-4-acetylbenzyl alcohol; 1-Acetyl-3-bromo-4-(hydroxymethyl)benzene; Ethanone, 1-[3-bromo-4-(hydroxymethyl)phenyl]-
EINECS	Contact for details

Quality Control

Our 1-(3-Bromo-4-(Hydroxymethyl)Phenyl)Ethanone is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality attributes. Our commitment to reliable supply and batch-to-batch reproducibility supports your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.