Description

5-Bromo-1-Chloro-3-Fluoro-2-(Trifluoromethoxy)Benzene is a high-purity, multi-halogenated benzene derivative designed for advanced chemical synthesis. This compound serves as a critical building block in the development of complex molecules, offering unique reactivity and structural features. It is primarily utilized by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging its halogenated structure for bioactivity.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution to introduce complex aromatic motifs.
• Fluorine Chemistry: Valued in medicinal chemistry for its trifluoromethoxy and fluorine groups, which can improve metabolic stability, lipophilicity, and bioavailability of lead compounds.

Basic Information

Product Name	5-Bromo-1-Chloro-3-Fluoro-2-(Trifluoromethoxy)Benzene
CAS No.	1417566-38-1
Molecular Formula	C7H2BrClF4O
Molecular Weight	293.44 g/mol
Synonyms	1-Bromo-3-chloro-5-fluoro-2-(trifluoromethoxy)benzene; 2-Bromo-4-chloro-6-fluoro-1-(trifluoromethoxy)benzene; Benzene, 5-bromo-1-chloro-3-fluoro-2-(trifluoromethoxy)-; 5-Bromo-1-chloro-3-fluoro-2-(trifluoromethoxy)benzene; 1417566-38-1; 2-Trifluoromethoxy-5-bromo-1-chloro-3-fluorobenzene
EINECS	Contact for details

Quality Control

Our production of 5-Bromo-1-Chloro-3-Fluoro-2-(Trifluoromethoxy)Benzene adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.