Description

1-(2-(Difluoromethyl)Phenyl)Ethanone is a specialized fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. Its core value lies in the strategic incorporation of the difluoromethyl group, which can profoundly influence the physicochemical and metabolic properties of target molecules. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly where fluorination is used to modulate lipophilicity, metabolic stability, and bioavailability.
• Agrochemical Synthesis: Serves as a precursor in the manufacture of advanced pesticides and herbicides, where the difluoromethyl moiety can enhance biological activity and environmental profile.
• Material Science Research: Used in the synthesis of fluorinated organic materials, such as liquid crystals or polymers, for specialized electronic or optical applications.
• Chemical Biology Probes: Employed in the design and synthesis of fluorinated probes and tags for studying biological mechanisms and interactions.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	1-(2-(Difluoromethyl)Phenyl)Ethanone
CAS No.	1417510-96-3
Molecular Formula	C9H8F2O
Molecular Weight	170.16 g/mol
Synonyms	2'-Difluoromethylacetophenone; 1-[2-(Difluoromethyl)phenyl]ethan-1-one; α,α-Difluoro-o-methylacetophenone; o-(Difluoromethyl)acetophenone; 2-Acetylbenzylidene Difluoride; (2-(Difluoromethyl)phenyl)(methyl)methanone
EINECS	Contact for details

Quality Control

Our 1-(2-(Difluoromethyl)Phenyl)Ethanone is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, documenting all critical quality attributes to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0% (Standard Grade)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.