Description

2-Bromo-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzaldehyde is a high-value, multi-functional boronic ester derivative that serves as a critical building block in modern synthetic chemistry. Its core value proposition lies in enabling precise carbon-carbon bond formation, a fundamental step in constructing complex molecular architectures. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-purity intermediates for Suzuki-Miyaura cross-coupling reactions and other palladium-catalyzed transformations.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for constructing biaryl and heterobiaryl scaffolds common in drug discovery.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides that require specific halogenated and boronate-functionalized aromatic systems.
• Material Science Research: Employed in the creation of organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, where its aldehyde and boronate groups allow for further functionalization.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands and organometallic catalysts used in asymmetric synthesis.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological processes, leveraging its reactive aldehyde group for bioconjugation.
• Polymer Chemistry: Acts as a monomer or cross-linking agent in the production of specialty polymers with tailored properties.

Basic Information

Product Name	2-Bromo-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzaldehyde
CAS No.	1417200-36-2
Molecular Formula	C13H16BBrO3
Molecular Weight	311.98 g/mol
Synonyms	2-Bromo-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde; 5-Bromo-2-formylphenylboronic acid pinacol ester; (2-Bromo-5-formylphenyl)boronic acid pinacol ester; 2-Bromo-5-(pinacolatoboryl)benzaldehyde; Pinacol 2-bromo-5-formylphenylboronate; [2-Bromo-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]methanal
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzaldehyde is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency suitable for sensitive cross-coupling reactions. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.