Description

2-Methyl-5-(Methoxycarbonyl)Pyridine-3-Boronic Acid Pinacol Ester is a high-value, protected boronic acid derivative crucial for modern synthetic chemistry. This compound matters as a key building block in cross-coupling reactions, enabling the efficient construction of complex heterocyclic scaffolds. Pharmaceutical, agrochemical, and advanced materials researchers need it for developing active ingredients and functional molecules. Its stability as a pinacol ester makes it a preferred reagent for Suzuki-Miyaura coupling and other metal-catalyzed transformations.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those containing functionalized pyridine cores for kinase inhibitors and other therapeutic agents.
• Agrochemical Synthesis: Used in the research and development of advanced crop protection agents and herbicides that require specific heterocyclic structures.
• Material Science Research: Serves as a building block for creating organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components for organic light-emitting diodes (OLEDs).
• Suzuki-Miyaura Cross-Coupling: The primary application is as a stable boronate reagent for forming carbon-carbon bonds between the pyridine ring and various aryl or vinyl halides.
• Chemical Biology & Probe Development: Utilized in the design and synthesis of molecular probes and tags for studying biological systems.
• Custom Synthesis & Contract Manufacturing: An essential starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing complex organic molecules for clients.

Basic Information

Product Name	2-Methyl-5-(Methoxycarbonyl)Pyridine-3-Boronic Acid Pinacol Ester
CAS No.	1417200-25-9
Molecular Formula	C14H20BNO4
Molecular Weight	277.12 g/mol
Synonyms	(5-(Methoxycarbonyl)-2-methylpyridin-3-yl)boronic acid pinacol ester; 3-Borono-5-(methoxycarbonyl)-2-methylpyridine pinacol ester; 2-Methyl-5-(methoxycarbonyl)pyridine-3-boronic acid pinacol ester; 5-Methoxycarbonyl-2-methyl-3-pyridineboronic acid pinacol ester; Pinacol [5-(methoxycarbonyl)-2-methyl-3-pyridyl]boronate; 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-5-(methoxycarbonyl)-2-methylpyridine
EINECS	Contact for details

Quality Control

Our 2-Methyl-5-(Methoxycarbonyl)Pyridine-3-Boronic Acid Pinacol Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality systems are designed to meet the stringent requirements of pharmaceutical intermediate production, supporting our clients' regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed under an inert atmosphere to maintain stability and prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.