Description

1-[2-Chloro-4-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Ethan-1-One is a high-purity, synthetically valuable boronic ester derivative. This compound serves as a critical advanced pharmaceutical intermediate (API) and a versatile building block in modern organic synthesis, particularly for cross-coupling reactions. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries who require reliable, high-quality precursors for complex molecule construction.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) via Suzuki-Miyaura cross-coupling reactions.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides.
• Material Science Research: Serves as a building block for creating organic electronic materials, such as OLEDs and semiconductors.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands and organometallic catalysts.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for biological target identification and validation.
• Custom Synthesis: A fundamental starting material for contract research organizations (CROs) and CDMOs performing bespoke chemical synthesis.

Basic Information

Product Name	1-[2-Chloro-4-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Ethan-1-One
CAS No.	1417036-32-8
Molecular Formula	C14H18BClO3
Molecular Weight	280.55 g/mol
Synonyms	2-Chloro-4-acetylphenylboronic acid pinacol ester; 1-[2-Chloro-4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]ethanone; 2'-Chloro-4'-acetylphenylboronic acid pinacol ester; (2-Chloro-4-acetylphenyl)boronic acid pinacol ester; 1417036-32-8; 2-Chloro-4-acetylbenzeneboronic acid pinacol ester; 4-Acetyl-2-chlorophenylboronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our production of 1-[2-Chloro-4-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Ethan-1-One adheres to stringent internal quality standards to ensure batch-to-batch consistency and reliability for your synthetic processes. Each lot is characterized by advanced analytical techniques including NMR, HPLC, and GC-MS. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation and to minimize degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.