Description

3-Methoxy-4-Methylphenylboronic Acid, Pinacol Ester is a high-purity, protected boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for drug discovery and fine chemical synthesis.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds between aryl halides and this boronic ester, crucial for synthesizing biaryl structures found in active pharmaceutical ingredients (APIs).
• Pharmaceutical Intermediate Synthesis: Used in the research and development of novel drug candidates, particularly in constructing complex aromatic and heteroaromatic scaffolds.
• Agrochemical Manufacturing: Employed in the synthesis of advanced herbicides, fungicides, and insecticides that require specific substituted phenyl groups.
• Ligand and Catalyst Development: Acts as a precursor for creating specialized ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Research: Utilized in the development of organic electronic materials, such as polymers for OLEDs and organic photovoltaics, due to its functionalized aromatic core.
• Chemical Biology & Proteomics: Can be used to create molecular probes and tags for studying biological systems and protein interactions.

Basic Information

Item	Details
Product Name	3-Methoxy-4-Methylphenylboronic Acid, Pinacol Ester
CAS No.	1417036-28-2
Molecular Formula	C14H21BO3
Molecular Weight	248.13 g/mol
Synonyms	3-Methoxy-4-methylbenzeneboronic acid pinacol ester; (3-Methoxy-4-methylphenyl)boronic acid pinacol ester; 2-(3-Methoxy-4-methylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4-Methyl-3-methoxyphenylboronic acid pinacol ester; Pinacol (3-Methoxy-4-methylphenyl)boronate; 3-Methoxy-p-tolylboronic acid pinacol ester
EINECS	Contact for details

Quality Control

Every batch of 3-Methoxy-4-Methylphenylboronic Acid, Pinacol Ester is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.