Description

Benzamide, n-(1,1-Dimethylethyl)-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)- is a high-value, functionalized organic intermediate featuring a boronic ester pinacol group. This compound is critical for enabling Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology in modern synthetic chemistry for forming carbon-carbon bonds. It is primarily sought after by research and development chemists in the pharmaceutical and advanced materials sectors who require reliable, high-purity building blocks for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly for creating biaryl structures common in many therapeutic agents.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that require specific, complex aromatic frameworks.
• Material Science Research: Serves as a monomer or precursor in the development of organic electronic materials, such as polymers for OLEDs (Organic Light-Emitting Diodes) and OFETs (Organic Field-Effect Transistors).
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for catalysis or as a scaffold for creating novel metal-organic complexes.
• Chemical Biology & Proteomics: Can be utilized in the synthesis of molecular probes and tools for studying biological processes and protein interactions.
• Academic & Industrial R&D: A versatile reagent for methodological development and exploratory synthesis in both university laboratories and corporate R&D centers.

Basic Information

Product Name	Benzamide, n-(1,1-Dimethylethyl)-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-
CAS No.	1416775-83-1
Molecular Formula	C17H26BNO3
Molecular Weight	303.21 g/mol
Synonyms	3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-N-(tert-butyl)benzamide; N-tert-Butyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide; tert-Butyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide; 3-Bpin-N-t-butylbenzamide; 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-N-(1,1-dimethylethyl)benzamide
EINECS	Contact for details

Quality Control

Every batch of our Benzamide boronic ester pinacol is manufactured and analyzed under strict quality management protocols to ensure high purity and batch-to-batch consistency, which is essential for sensitive cross-coupling reactions. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with industry standards. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.