Description

5-Isopropoxy-2-Methylphenylboronic Acid, Pinacol Ester is a high-purity, protected boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the precise construction of complex molecular architectures. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides requiring specific aryl-aryl linkages.
• Material Science Research: Employed in the creation of organic electronic materials, such as polymers for OLEDs and organic photovoltaics.
• Chemical Biology & Proteomics: Acts as a versatile handle for bioconjugation and the synthesis of molecular probes and inhibitors.
• Catalyst & Ligand Development: Serves as a starting material for synthesizing novel ligands and organometallic catalysts.
• Custom Synthesis & Contract Manufacturing: A valuable reagent for custom synthesis houses and CROs/CMOs serving the global life sciences market.

Basic Information

Product Name	5-Isopropoxy-2-Methylphenylboronic Acid, Pinacol Ester
CAS No.	1416723-00-6
Molecular Formula	C16H25BO3
Molecular Weight	276.18 g/mol
Synonyms	2-Methyl-5-(propan-2-yloxy)phenylboronic acid pinacol ester; (5-Isopropoxy-2-methylphenyl)boronic acid pinacol ester; B-[5-(1-Methylethoxy)-2-methylphenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 5-Isopropoxy-2-methylbenzeneboronic acid pinacol ester; Pinacol (5-isopropoxy-2-methylphenyl)boronate; Boronic acid, B-[5-(1-methylethoxy)-2-methylphenyl]-, 4,4,5,5-tetramethyl-1,3,2-dioxaborolane ester
EINECS	Contact for details

Quality Control

Our 5-Isopropoxy-2-Methylphenylboronic Acid, Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC analysis, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) with lot-specific data are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). The product is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.