Description

2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-4-(Trifluoromethyl)Benzaldehyde is a high-value, synthetically versatile organoboron building block. This compound is essential for facilitating Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology in modern organic synthesis. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially those containing trifluoromethyl and biaryl motifs.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides with enhanced properties.
• Material Science Research: Serves as a precursor for organic electronic materials, such as OLED (Organic Light-Emitting Diode) emitters and charge transport materials.
• Ligand and Catalyst Development: Employed in the creation of novel ligands and organometallic catalysts for asymmetric synthesis.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological systems.
• Academic & Industrial R&D: A critical reagent for method development and exploring new synthetic pathways in organic chemistry laboratories.

Basic Information

Product Name	2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-4-(Trifluoromethyl)Benzaldehyde
CAS No.	1416721-24-8
Molecular Formula	C14H16BF3O3
Molecular Weight	300.09 g/mol
Synonyms	4-(Trifluoromethyl)-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde; 2-Formyl-5-(trifluoromethyl)phenylboronic acid pinacol ester; (2-Formyl-5-(trifluoromethyl)phenyl)boronic acid pinacol ester; 4-(Trifluoromethyl)-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenecarboxaldehyde; 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-4-(trifluoromethyl)benzaldehyde; PINACOL 2-FORMYL-5-(TRIFLUOROMETHYL)PHENYLBORONATE
EINECS	Contact for details

Quality Control

Our 2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-4-(Trifluoromethyl)Benzaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided to guarantee the material meets your research and process requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, it is recommended to handle the material under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to minimize exposure to ambient moisture. Recommended storage temperature: 2-8°C for prolonged stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.