Description

(5-Methylpyridazin-4-Yl)Boronic Acid Pinacol Ester is a high-purity boronic ester derivative, a crucial building block in modern synthetic organic chemistry. Its primary value lies in enabling efficient and selective Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex molecular architectures. This advanced intermediate is essential for researchers and process chemists in the pharmaceutical, agrochemical, and material science industries, facilitating the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting a range of therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new pesticides, herbicides, and fungicides by enabling the formation of specific carbon-carbon bonds.
• Material Science Research: Employed in the creation of organic electronic materials, ligands for catalysts, and other functional organic compounds.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a stable, air-handleable organoboron reagent for palladium-catalyzed coupling with aryl or vinyl halides.
• Chemical Biology Probes: Facilitates the synthesis of labeled compounds and molecular probes for biological target identification and validation.
• Process Chemistry & Scale-Up: Suitable for use in route development and optimization from laboratory to pilot plant scale, owing to its stability profile.

Basic Information

Product Name	(5-Methylpyridazin-4-Yl)Boronic Acid Pinacol Ester
CAS No.	1416720-48-3
Molecular Formula	C₁₁H₁₇BN₂O₂
Molecular Weight	220.08 g/mol
Synonyms	4,4,5,5-Tetramethyl-2-(5-methyl-4-pyridazinyl)-1,3,2-dioxaborolane; 2-(5-Methylpyridazin-4-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; (5-Methyl-4-pyridazinyl)boronic acid pinacol ester; 5-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridazine; Boronic acid, B-(5-methyl-4-pyridazinyl)-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our (5-Methylpyridazin-4-Yl)Boronic Acid Pinacol Ester is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is characterized by advanced analytical techniques including NMR, HPLC, and GC-MS. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term stability, especially after opening the original packaging. Recommended storage temperature is 2-8°C for prolonged shelf life.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.