Description

Butyl Paraben-13C6 CAS NO 1416711-53-9 is a stable isotope-labeled analog of butyl paraben, where six carbon atoms are replaced with the carbon-13 isotope. This compound is essential as an internal standard for the precise and accurate quantification of butyl paraben in complex matrices using advanced analytical techniques like LC-MS/MS and GC-MS. It is critically needed by analytical laboratories, contract research organizations (CROs), and pharmaceutical manufacturers engaged in method development, quality control, and regulatory compliance testing for preservative analysis.

Application

• Internal Standard for Mass Spectrometry: Used for the accurate quantification of butyl paraben in LC-MS/MS and GC-MS methods, correcting for matrix effects and instrument variability.
• Pharmaceutical Quality Control: Essential for analyzing preservative content and degradation products in drug formulations, creams, and ointments to ensure batch consistency and safety.
• Cosmetic & Personal Care Product Testing: Enables reliable measurement of butyl paraben levels in lotions, shampoos, and makeup to verify compliance with regional concentration limits.
• Food & Beverage Analysis: Supports the detection and quantification of butyl paraben as a preservative in food products and beverages for safety assessment.
• Environmental & Bioanalytical Research: Facilitates trace-level detection of parabens in environmental water samples, biological fluids, and toxicology studies.
• Method Development & Validation: Serves as a critical reference material for developing, optimizing, and validating new analytical methods in compliance with ICH, FDA, and EMA guidelines.
• Stability Studies: Employed in forced degradation and shelf-life studies of products containing butyl paraben to monitor preservative efficacy over time.

Basic Information

Product Name	Butyl Paraben-13C6
CAS No.	1416711-53-9
Molecular Formula	¹³C₆H₄(OH)COOC₄H₉
Molecular Weight	~202.19 g/mol (for ¹³C₆ labeled form)
Synonyms	Butyl 4-hydroxybenzoate-13C6; Butyl paraben-13C6; Butyl 4-hydroxybenzoate-13C6 (ring-labeled); 4-Hydroxybenzoic acid butyl ester-13C6; Butyl paraben (ring-13C6); n-Butyl paraben-13C6; Butyl paraben (13C6); Benzoic acid, 4-hydroxy-, butyl ester-13C6
EINECS	Contact for details

Quality Control

Our Butyl Paraben-13C6 is manufactured and tested under strict quality systems. Each batch is characterized to ensure high chemical and isotopic purity, critical for its role as an analytical standard. Comprehensive testing includes assay by HPLC, isotopic enrichment by MS, and identification by IR and NMR spectroscopy. A detailed Certificate of Analysis (COA) is provided with each shipment, containing batch-specific data. Our quality commitment aligns with the needs of GMP/GLP-compliant laboratories.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment	≥ 99 atom % ¹³C (on labeled positions)
Chemical Purity (by HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.