Description

3-Methanesulfinylphenylboronic Acid, Pinacol Ester is a high-purity, organoboron building block specifically designed for advanced synthetic chemistry. This compound is crucial for facilitating Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex biaryl and heterobiaryl structures. It is an essential reagent for researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries who require reliable, high-quality intermediates for drug discovery and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing sulfoxide and biaryl motifs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific aryl-aryl couplings.
• Material Science Research: Employed in the creation of organic electronic materials, such as those for OLEDs and semiconductors, where precise molecular architecture is critical.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands and catalysts used in asymmetric synthesis and other catalytic processes.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological systems and mechanisms.
• Custom Synthesis and Contract Manufacturing: A vital reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.

Basic Information

Item	Details
Product Name	3-Methanesulfinylphenylboronic Acid, Pinacol Ester
CAS No.	1416367-04-8
Molecular Formula	C13H19BO3S
Molecular Weight	266.16 g/mol
Synonyms	3-(Methylsulfinyl)phenylboronic acid pinacol ester; (3-(Methylsulfinyl)phenyl)boronic acid pinacol ester; [3-(Methanesulfinyl)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 3-Methylsulfinylbenzeneboronic acid pinacol ester; Boronic acid, B-[3-(methylsulfinyl)phenyl]-, 1,1-dimethylethyl ester; 3-(Methylsulfinyl)benzeneboronic acid pinacol ester; Pinacol 3-(methylsulfinyl)benzeneboronate
EINECS	Contact for details

Quality Control

Every batch of 3-Methanesulfinylphenylboronic Acid, Pinacol Ester is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing results from HPLC, NMR, and MS analyses. Our quality commitment aligns with cGMP principles for advanced pharmaceutical intermediates, ensuring traceability and reliability for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.