Description

n-Cyclopropyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenesulfonamide is a high-purity boronic ester derivative, a critical building block in modern synthetic organic chemistry. Its value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex biaryl and heterobiaryl scaffolds. This advanced intermediate is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) targeting a range of therapeutic areas.
• Agrochemical Research: Used in the discovery and development of new herbicides, fungicides, and insecticides.
• Material Science: Enables the creation of novel organic electronic materials, ligands for catalysts, and liquid crystals.
• Suzuki-Miyaura Cross-Coupling: Serves as a versatile boronic ester coupling partner for the formation of carbon-carbon bonds under mild conditions.
• Medicinal Chemistry: Facilitates rapid structure-activity relationship (SAR) studies and library synthesis for drug discovery programs.
• Chemical Biology: Used in the synthesis of molecular probes and bioconjugates for biological target identification.

Basic Information

Product Name	n-Cyclopropyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenesulfonamide
CAS No.	1416367-02-6
Molecular Formula	C15H22BNO4S
Molecular Weight	323.22 g/mol
Synonyms	3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-N-cyclopropylbenzenesulfonamide; Benzenesulfonamide, N-cyclopropyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; N-Cyclopropyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenesulfonamide; 3-Boronic acid, benzenesulfonamide, N-cyclopropyl-, 1,3,2-dioxaborolane ester; Pinacol ester of 3-(N-Cyclopropylsulfamoyl)phenylboronic acid
EINECS	Contact for details

Quality Control

Our n-Cyclopropyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenesulfonamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our commitment to quality supports cGMP-compliant workflows for advanced research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and decomposition. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.