Description

2-Methoxy-4-(4-Trifluoromethyl-Piperidin-1-Yl)-Aniline is a high-purity, advanced pharmaceutical intermediate featuring a unique trifluoromethyl-piperidine-aniline scaffold. This compound is of significant commercial interest for its role in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular frameworks. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key building block for the research and synthesis of new drug candidates, especially in central nervous system (CNS) and oncology research.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, leveraging the biological activity of the trifluoromethyl and aniline groups.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in catalytic systems and metal-organic frameworks (MOFs).
• Material Science: Potential monomer or additive for advanced polymers and functional materials requiring specific optical or electronic properties.
• Chemical Biology Probes: Utilized in the design of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs offering bespoke chemical synthesis services.

Basic Information

Product Name	2-Methoxy-4-(4-Trifluoromethyl-Piperidin-1-Yl)-Aniline
CAS No.	1416352-07-2
Molecular Formula	C13H17F3N2O
Molecular Weight	274.28 g/mol
Synonyms	1-(4-Amino-3-methoxyphenyl)-4-(trifluoromethyl)piperidine; 4-(4-Trifluoromethyl-1-piperidinyl)-2-methoxyaniline; 2-Methoxy-4-[4-(trifluoromethyl)piperidin-1-yl]aniline; 2-Methoxy-4-(4-trifluoromethylpiperidin-1-yl)benzenamine; 1416352-07-2; 4-(4-Trifluoromethylpiperidin-1-yl)-2-methoxyaniline
EINECS	Contact for details

Quality Control

Our 2-Methoxy-4-(4-Trifluoromethyl-Piperidin-1-Yl)-Aniline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, confirming compliance with customer specifications and relevant industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.