Description

2-(2-Methoxy-5-Methylphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane CAS NO 1416165-54-2 is a high-purity, advanced boronic ester building block essential for modern synthetic chemistry. This compound matters for its role as a key coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. It is primarily needed by research and development teams in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Critical for synthesizing active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing complex biaryl motifs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides requiring specific aryl-aryl linkages.
• Material Science Research: Serves as a precursor for organic electronic materials, including polymers and small molecules for OLEDs and OFETs.
• Chemical Biology & Proteomics: Employed in the development of molecular probes and bioconjugation reagents.
• Catalyst & Ligand Development: Acts as a starting material for synthesizing novel ligands and organometallic catalysts.
• Custom Synthesis & Contract Manufacturing: A valuable building block for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	2-(2-Methoxy-5-Methylphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	1416165-54-2
Molecular Formula	C14H21BO3
Molecular Weight	248.13 g/mol
Synonyms	2-Methoxy-5-methylbenzeneboronic acid pinacol ester; (2-Methoxy-5-methylphenyl)boronic acid pinacol ester; 2-(2-Methoxy-5-methylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 5-Methyl-2-methoxyphenylboronic acid pinacol ester; Pinacol (2-methoxy-5-methylphenyl)boronate; 2-Methoxy-5-methylphenyl-Bpin; CAS 1416165-54-2
EINECS	Contact for details

Quality Control

Our 2-(2-Methoxy-5-Methylphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (GC)	≥98.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.