Description

4-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-1-(3-Trifluoromethyl-Benzyl)-1H-Pyrazole is a high-value, synthetically versatile organoboron building block, specifically a pyrazole-substituted pinacol boronic ester. This compound matters for its crucial role as a key intermediate in modern cross-coupling reactions, enabling the efficient synthesis of complex molecules. It is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers for developing active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: A critical building block in Suzuki-Miyaura cross-coupling reactions for constructing novel drug candidates, particularly in medicinal chemistry programs.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, leveraging the pyrazole and trifluoromethyl motifs for bioactivity.
• Material Science Research: Serves as a precursor for creating functional organic molecules used in organic light-emitting diodes (OLEDs) and liquid crystals.
• Chemical Biology Probes: Employed in the synthesis of labeled compounds and molecular probes for biochemical and diagnostic research applications.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke, high-value compounds on a commercial scale.

Basic Information

Product Name	4-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-1-(3-Trifluoromethyl-Benzyl)-1H-Pyrazole
CAS No.	1415825-08-9
Molecular Formula	C17H22BF3N2O2
Molecular Weight	354.18 g/mol
Synonyms	1-[(3-Trifluoromethyl)benzyl]-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole; 1-(3-(Trifluoromethyl)benzyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-[(3-trifluoromethylphenyl)methyl]pyrazole; 1-(3-Trifluoromethyl-benzyl)-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole; (1-(3-(Trifluoromethyl)benzyl)-1H-pyrazol-4-yl)boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 4-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-1-(3-Trifluoromethyl-Benzyl)-1H-Pyrazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability and batch-to-batch consistency, meeting the stringent requirements of pharmaceutical and fine chemical industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.