Description

Oleanolic Acid - 3-o-α-L-Rhamnosyl(1→6)β-D-Galactosyl(1→3)-β-D-Glucosyl(1→3)-α-L-Rhamnosyl(1→2)-α-L-Arabinoside is a highly specialized triterpenoid saponin derivative isolated from natural plant sources such as *Aralia elata* and related species, characterized by its complex oligosaccharide chain attached at the C-3 position of oleanolic acid. This compound exhibits enhanced bioavailability and targeted biological activity compared to its aglycone counterpart, making it particularly valuable for advanced phytopharmaceutical research and development. It is primarily sought by R&D laboratories, contract research organizations (CROs), and biopharmaceutical manufacturers engaged in anti-inflammatory, hepatoprotective, and antitumor mechanism studies.

Application

• Preclinical investigation of NF-κB and STAT3 signaling pathway modulation in oncology research
• Development of standardized botanical extracts for nutraceutical formulations targeting metabolic syndrome
• Reference standard for HPLC and LC-MS/MS quantification in herbal quality control laboratories
• Structure-activity relationship (SAR) studies on triterpenoid glycosides for novel drug candidate optimization
• Biological evaluation of saponin-mediated membrane permeabilization in drug delivery systems
• Stability and degradation kinetics modeling under accelerated stress conditions (light, humidity, temperature)

Basic Information

Product Name	Oleanolic Acid - 3-o-α-L-Rhamnosyl(1→6)β-D-Galactosyl(1→3)-β-D-Glucosyl(1→3)-α-L-Rhamnosyl(1→2)-α-L-Arabinoside
CAS No.	1415553-83-1
Molecular Formula	C59H94O27
Molecular Weight	1223.38 g/mol
Synonyms	Aralosidic Acid; Aralosidin A; Oleanolic acid 3-O-α-L-rhamnopyranosyl-(1→2)-α-L-arabinopyranoside-28-O-β-D-glucopyranosyl-(1→6)-β-D-galactopyranoside; 3-O-[α-L-Rhamnopyranosyl-(1→2)-α-L-arabinopyranosyl]-oleanolic acid 28-O-[β-D-glucopyranosyl-(1→6)-β-D-galactopyranoside]; Aralosidin A1; AE-1; NSC 771322; Triterpenoid Saponin AR-1
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request. Each batch is verified for identity (IR, NMR, HRMS), purity (HPLC ≥98.0%), residual solvents (GC), heavy metals (ICP-MS), and microbiological limits (where applicable). Testing adheres to ICH Q5, Q6A, and USP <1111> guidelines for botanical reference standards.

Storage

Preserve in a tightly closed container, protected from light. Store at 2–8 °C under inert atmosphere (nitrogen or argon) to prevent oxidation and hydrolysis. Due to its hygroscopic nature, maintain relative humidity below 30% and avoid repeated exposure to ambient air. Handle in a controlled environment with desiccated glove box or dry nitrogen purge when opening.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches certified reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	≤2.0% total impurities
Residual Solvents (GC)	Meets ICH Q3C limits
Water Content (Karl Fischer)	≤5.0%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.