Description

2-(4'-Bromobiphenyl-4-Yl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-purity boronic ester derivative, a critical building block in modern synthetic organic chemistry. Its primary value lies in enabling efficient carbon-carbon bond formation via the Suzuki-Miyaura cross-coupling reaction, a cornerstone methodology for pharmaceutical and advanced material synthesis. This compound is essential for researchers and process chemists in pharmaceutical R&D, agrochemical development, and the creation of organic electronic materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those containing biphenyl or extended aromatic systems.
• Agrochemical Synthesis: Used in the development of novel active ingredients for crop protection products.
• Material Science: Serves as a monomer or building block for organic light-emitting diodes (OLEDs), semiconductors, and liquid crystals.
• Chemical Research: A versatile reagent for academic and industrial research focused on palladium-catalyzed cross-coupling reactions.
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals and complex organic molecules.

Basic Information

Product Name	2-(4'-Bromobiphenyl-4-Yl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	1414997-84-4
Molecular Formula	C24H24BBrO2
Molecular Weight	435.17 g/mol
Synonyms	4'-Bromo-[1,1'-biphenyl]-4-ylboronic acid pinacol ester; 4-Bromo-4'-pinacolatoborylbiphenyl; 2-(4'-Bromobiphenyl-4-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4-Bromo-4'-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,1'-biphenyl; (4'-Bromo-[1,1'-biphenyl]-4-yl)boronic acid pinacol ester; 4'-Bromo-4-biphenylboronic acid pinacol ester; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-4'-bromobiphenyl
EINECS	Contact for details

Quality Control

Our 2-(4'-Bromobiphenyl-4-Yl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity suitable for sensitive coupling reactions. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity and impurity profiles. Our quality management system is designed to meet the stringent requirements of pharmaceutical R&D and fine chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or when opening the container to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.