Description

3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-2-Pyridinecarboxamide is a high-value boronic ester derivative, a key building block in modern synthetic chemistry. Its primary commercial value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used to create novel compounds for crop protection agents, including herbicides, fungicides, and insecticides.
• Material Science: Serves as a building block for organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Chemical Synthesis: Enables the formation of carbon-carbon bonds in complex molecule construction for fine chemicals and specialty polymers.
• Bioconjugation & Probe Development: Utilized in the creation of biochemical probes and labeling reagents for diagnostic and research applications.
• Library Synthesis for Drug Discovery: A valuable reagent for generating diverse compound libraries in high-throughput screening campaigns.

Basic Information

Product Name	3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-2-Pyridinecarboxamide
CAS No.	1412415-69-0
Molecular Formula	C13H19BN2O3
Molecular Weight	262.11 g/mol
Synonyms	2-Pyridinecarboxamide, 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)picolinamide; 3-Pinacolatoborylpicolinamide; 3-Boronopyridine-2-carboxamide pinacol ester; Picolinamide, 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 3-(Pinacolatoboryl)picolinamide
EINECS	Contact for details

Quality Control

Our 3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-2-Pyridinecarboxamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure high purity and consistent performance for sensitive cross-coupling reactions. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.