Description

2-Chloro-1-(4-Fluoro-2-Hydroxyphenyl)Ethanone is a high-purity, halogenated aromatic ketone building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily needed by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), crop protection agents, and novel materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory pathways.
• Agrochemical Synthesis: Serves as a building block for developing advanced herbicides and fungicides, leveraging its halogenated structure for bioactivity.
• Material Science Research: Used in the preparation of specialty polymers and liquid crystals where the introduction of fluorine and chlorine atoms modifies material properties.
• Chemical Research & Development: Employed in method development and as a standard in analytical chemistry for halogenated aromatic compounds.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis houses serving the pharmaceutical and specialty chemical industries.

Basic Information

Product Name	2-Chloro-1-(4-Fluoro-2-Hydroxyphenyl)Ethanone
CAS No.	1410792-94-7
Molecular Formula	C8H6ClFO2
Molecular Weight	188.58 g/mol
Synonyms	2-Chloro-1-(4-fluoro-2-hydroxyphenyl)ethan-1-one; 1-(4-Fluoro-2-hydroxyphenyl)-2-chloroethanone; 4'-Fluoro-2'-hydroxy-2-chloroacetophenone; 2-Chloro-4'-fluoro-2'-hydroxyacetophenone; α-Chloro-4-fluoro-2-hydroxyacetophenone; CAS 1410792-94-7
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-1-(4-Fluoro-2-Hydroxyphenyl)Ethanone is manufactured under strict quality management systems. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.