Description

8-Fluoro-1,3,4,5-Tetrahydro-Azepino[5,4,3-Cd]Indol-6-One is a high-purity, advanced pharmaceutical intermediate belonging to the azepinoindolone class of heterocyclic compounds. Its core value lies in its role as a critical building block for the synthesis of novel, biologically active molecules, particularly in central nervous system (CNS) and oncology research. This compound is essential for medicinal chemists and process development scientists in pharmaceutical R&D and fine chemical manufacturing who require reliable, high-quality intermediates for drug discovery and development programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential therapeutic agents targeting neurological disorders.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies to optimize drug candidate potency and selectivity.
• Process Chemistry Development: Serves as a critical intermediate for scaling up synthetic routes under current Good Manufacturing Practice (cGMP) conditions.
• Biochemical Tool Compound: Utilized in vitro and in vivo to study specific biological pathways and receptor interactions.
• Library Synthesis for High-Throughput Screening: Enables the creation of diverse compound libraries to identify new lead molecules.
• Academic Research: Employed in university and institutional labs for fundamental research in organic synthesis and pharmacology.

Basic Information

Product Name	8-Fluoro-1,3,4,5-Tetrahydro-Azepino[5,4,3-Cd]Indol-6-One
CAS No.	1408282-26-7
Molecular Formula	C12H11FN2O
Molecular Weight	218.23 g/mol
Synonyms	8-Fluoro-1,3,4,5-tetrahydroazepino[5,4,3-cd]indol-6(2H)-one; 8-Fluoro-2,3,4,5-tetrahydro-1H-azepino[5,4,3-cd]indol-6-one; Azepino[5,4,3-cd]indol-6-one, 8-fluoro-1,3,4,5-tetrahydro-; 1408282-26-7; 8-Fluoro-tetrahydro-azepinoindolone; 8-F-Azepinoindolone
EINECS	Contact for details

Quality Control

Our 8-Fluoro-1,3,4,5-Tetrahydro-Azepino[5,4,3-Cd]Indol-6-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the stringent requirements for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and full analytical data is provided with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.