Description

4-(Methoxymethoxy)-3-(Trifluoroacetyl)Chlorobenzene is a high-value, multi-functional aromatic intermediate featuring both a reactive chlorobenzene core and a trifluoroacetyl group. This compound is critical for the synthesis of advanced pharmaceutical ingredients and agrochemicals, where its unique structure enables the introduction of fluorine atoms and complex side chains. It is primarily sought by R&D chemists and process development teams in the fine chemical, pharmaceutical, and agrochemical sectors for constructing novel active molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced herbicides and fungicides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and material science.
• Fluorinated Compound Research: Essential for introducing the trifluoroacetyl moiety into complex organic frameworks in academic and industrial R&D.
• Fine Chemical Production: Employed in multi-step syntheses to produce specialty chemicals for electronics and advanced materials.

Basic Information

Product Name	4-(Methoxymethoxy)-3-(Trifluoroacetyl)Chlorobenzene
CAS No.	1408279-24-2
Molecular Formula	C10H8ClF3O3
Molecular Weight	268.62 g/mol
Synonyms	1-Chloro-4-(methoxymethoxy)-2-(trifluoroacetyl)benzene; 2-Chloro-5-(methoxymethoxy)phenyl trifluoromethyl ketone; 3-Trifluoroacetyl-4-methoxymethoxychlorobenzene; 4-Methoxymethoxy-3-trifluoroacetylchlorobenzene; 2-Chloro-α,α,α-trifluoro-5-(methoxymethoxy)acetophenone; 5-Chloro-2-(methoxymethoxy)phenyl trifluoromethyl ketone
EINECS	Contact for details

Quality Control

Our 4-(Methoxymethoxy)-3-(Trifluoroacetyl)Chlorobenzene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and current industry standards for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.