Description

Methyl 3-Oxo-1-Methyl-Cyclobutanecarboxylate is a high-purity, functionalized cyclobutane derivative that serves as a versatile and valuable synthetic building block in advanced organic chemistry. Its unique strained-ring structure combined with reactive keto and ester functionalities makes it an essential precursor for constructing complex molecular architectures. This compound is primarily sought after by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and specialty chemical sectors for developing novel active ingredients and performance materials.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly for constructing constrained, sp3-rich scaffolds that can improve potency and metabolic stability.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the cyclobutane ring can impart unique biological activity and selectivity.
• Organic Synthesis Building Block: Employed in [2+2] cycloaddition reactions, ring-expansion strategies, and as a precursor for γ-amino acids or other functionalized small molecules.
• Material Science Precursor: Potential monomer or cross-linking agent for creating polymers with tailored thermal and mechanical properties derived from the rigid cyclobutane core.
• Flavor & Fragrance Chemistry: Serves as an intermediate for synthesizing complex musk compounds and other specialty aroma chemicals.

Basic Information

Product Name	Methyl 3-Oxo-1-Methyl-Cyclobutanecarboxylate
CAS No.	1408075-88-6
Molecular Formula	C8H12O3
Molecular Weight	156.18 g/mol
Synonyms	Methyl 1-methyl-3-oxocyclobutanecarboxylate; 3-Oxo-1-methylcyclobutanecarboxylic acid methyl ester; 1-Methyl-3-oxocyclobutanecarboxylic Acid Methyl Ester; Methyl 3-oxo-1-methylcyclobutanecarboxylate; Cyclobutanecarboxylic acid, 3-oxo-1-methyl-, methyl ester
EINECS	Contact for details

Quality Control

Our production of Methyl 3-Oxo-1-Methyl-Cyclobutanecarboxylate adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is fully characterized and undergoes rigorous analytical testing. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition. For long-term storage, consider maintaining under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.