Description

3,3-Dimethoxy-1-Methyl-Cyclobutanecarboxylic Acid is a specialized cyclobutane derivative featuring a carboxylic acid group and methoxy substituents, making it a valuable multifunctional building block in advanced organic synthesis. Its unique sterically constrained structure is prized for constructing complex molecular frameworks with specific spatial orientations. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the cyclobutane ring can contribute to unique biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Investigated as a monomer or cross-linking agent for producing polymers with tailored thermal and mechanical properties.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes for studying enzyme mechanisms and protein interactions.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes in fine chemical manufacturing.

Basic Information

Item	Details
Product Name	3,3-Dimethoxy-1-Methyl-Cyclobutanecarboxylic Acid
CAS No.	1408075-28-4
Molecular Formula	C9H16O4
Molecular Weight	188.22 g/mol
Synonyms	1-Methyl-3,3-dimethoxycyclobutanecarboxylic acid; 3,3-Dimethoxy-1-methylcyclobutanecarboxylic acid; Cyclobutanecarboxylic acid, 1-methyl-3,3-dimethoxy-; 1408075-28-4; 3,3-Dimethoxy-1-methyl-cyclobutanecarboxylic acid; 1-Methyl-3,3-bis(methoxy)cyclobutanecarboxylic acid
EINECS	Contact for details

Quality Control

Every batch of 3,3-Dimethoxy-1-Methyl-Cyclobutanecarboxylic Acid is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the identity, purity, and consistency required for sensitive research and scale-up applications. A Certificate of Analysis (COA) detailing specifications such as assay (by HPLC), identity confirmation (by IR/NMR), and impurity profiles is supplied with each shipment. Our quality commitment supports compliance with cGMP and ISO standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as oxidizing agents. For long-term storage, consider holding under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.