Description

4-Hydroxymethyl-3-Methoxyphenylboronic Acid Pinacol Ester is a high-purity, protected boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical, stable building block for Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those containing substituted biphenyl or heterobiaryl motifs.
• Agrochemical Synthesis: Used to create novel active ingredients for crop protection products through palladium-catalyzed cross-coupling.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in asymmetric catalysis and material science.
• OLED and Electronic Material Research: Employed in the construction of organic semiconductors and light-emitting materials for display technologies.
• Polymer Chemistry: Incorporated into polymer backbones to create functional materials with specific electronic or mechanical properties.
• Chemical Biology & Probe Development: Utilized for labeling and modifying biomolecules or creating activity-based probes for research.

Basic Information

Product Name	4-Hydroxymethyl-3-Methoxyphenylboronic Acid Pinacol Ester
CAS No.	1404094-91-2
Molecular Formula	C14H21BO4
Molecular Weight	264.13 g/mol
Synonyms	(4-(Hydroxymethyl)-3-methoxyphenyl)boronic acid pinacol ester; 3-Methoxy-4-(hydroxymethyl)benzeneboronic acid pinacol ester; 4-(Hydroxymethyl)-3-methoxybenzeneboronic acid pinacol ester; Pinacol (4-(hydroxymethyl)-3-methoxyphenyl)boronate; B-[4-(Hydroxymethyl)-3-methoxyphenyl]-5,5-dimethyl-1,3,2-dioxaborinane; 4-(Hydroxymethyl)-3-methoxy phenylboronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 4-Hydroxymethyl-3-Methoxyphenylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.