Description

2-(6-Bromo-2-Naphthalenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane CAS NO 1404070-35-4 is a high-purity, advanced pharmaceutical intermediate and versatile building block in organic synthesis. Its core value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone of modern medicinal chemistry and materials science. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and OLED materials industries who require reliable, high-quality boronic ester reagents for complex molecule construction.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in oncology and central nervous system (CNS) drug discovery programs.
• Suzuki-Miyaura Cross-Coupling: A critical reagent for palladium-catalyzed coupling reactions to create biaryl and heterobiaryl structures, which are prevalent in many drug molecules.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides, fungicides, and insecticides with complex aromatic backbones.
• Organic Light-Emitting Diode (OLED) Materials: Serves as a precursor for creating naphthalene-based electron-transport materials and host materials for display and lighting technologies.
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Polymer Chemistry: A monomer for constructing conjugated polymers with specific electronic properties for organic electronics.
• Chemical Research & Development: A versatile tool for academic and industrial R&D labs exploring new synthetic methodologies and complex molecular architectures.

Basic Information

Product Name	2-(6-Bromo-2-Naphthalenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	1404070-35-4
Molecular Formula	C₁₆H₁₈BBrO₂
Molecular Weight	333.03 g/mol
Synonyms	6-Bromo-2-naphthaleneboronic acid pinacol ester; (6-Bromonaphthalen-2-yl)boronic acid pinacol ester; 2-(6-Bromonaphthalen-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 6-Bromo-2-naphthylboronic acid pinacol ester; Pinacol (6-bromo-2-naphthyl)boronate; 6-Bromo-2-naphthaleneboronic acid, pinacol ester; B-(6-Bromo-2-naphthyl)boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 2-(6-Bromo-2-Naphthalenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency suitable for sensitive coupling reactions. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain optimal stability and reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.