Description

(S)-Hesperetin Benzyl Ether is a high-purity, chiral derivative of the natural flavonoid hesperetin, specifically functionalized with a benzyl protecting group. This compound is of significant value as a key synthetic intermediate and reference standard in advanced pharmaceutical and nutraceutical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, cosmetic, and fine chemical industries for applications in drug discovery, metabolic studies, and the synthesis of bioactive flavonoid analogs.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral building block in the synthesis of novel drug candidates targeting inflammation, metabolic disorders, and oxidative stress.
• Reference Standard: Used as a high-purity analytical standard for method development and quality control in HPLC and LC-MS analysis of flavonoid-based products.
• Biochemical Research: Employed in studies investigating the structure-activity relationships (SAR) of flavanones, particularly those related to bioavailability and receptor binding.
• Nutraceutical Development: Acts as a precursor or model compound for developing enhanced-activity or improved-stability flavonoid ingredients for dietary supplements.
• Cosmetic Actives Research: Utilized in R&D for creating stable, bioavailable flavonoid derivatives with potential skin-protective and anti-aging properties.
• Process Chemistry: Applied in route scouting and optimization for the scalable production of chiral flavonoid derivatives under GMP-like conditions.

Basic Information

Product Name	(S)-Hesperetin Benzyl Ether
CAS No.	1403990-90-8
Molecular Formula	C23H20O6
Molecular Weight	392.40 g/mol
Synonyms	(S)-5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4-chromanone 7-Benzyl Ether; (2S)-5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one 7-(Phenylmethyl) Ether; 7-O-Benzylhesperetin; (S)-Hesperetin 7-Benzyl Ether; Benzylhesperetin; Hesperetin Benzyl Ether (S-enantiomer)
EINECS	Contact for details

Quality Control

Our (S)-Hesperetin Benzyl Ether is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric purity, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥97.0%
Chiral Purity (HPLC)	≥98.0% ee
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.