Description

5-[3-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Phenyl]-Isoxazole is a high-purity boronic ester derivative, a critical building block in modern synthetic organic chemistry. Its value lies in enabling efficient, selective cross-coupling reactions, which are fundamental for constructing complex molecular architectures. This advanced intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries, particularly in the development of active pharmaceutical ingredients (APIs) and functional organic materials.

Application

• Pharmaceutical Intermediate: Key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Research: Used in the discovery and development of new herbicides, fungicides, and insecticides with improved efficacy.
• Organic Electronic Materials: Building block for creating conjugated polymers and small molecules used in OLEDs, organic photovoltaics (OPVs), and sensors.
• Ligand Synthesis: Intermediate for the preparation of specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized in the synthesis of bioconjugates and molecular probes for target identification and validation.
• Academic & Industrial R&D: Serves as a versatile reagent for method development and exploring new synthetic pathways in laboratory settings.

Basic Information

Product Name	5-[3-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Phenyl]-Isoxazole
CAS No.	1403469-17-9
Molecular Formula	C15H18BNO3
Molecular Weight	271.12 g/mol
Synonyms	3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl isoxazole; 5-[3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-1,2-oxazole; 3-(Isoxazol-5-yl)phenylboronic acid pinacol ester; (3-(Isoxazol-5-yl)phenyl)boronic acid pinacol ester; 1403469-17-9; 5-(3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)isoxazole
EINECS	Contact for details

Quality Control

Our 5-[3-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Phenyl]-Isoxazole is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and LC-MS, to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes to support your R&D and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when opening the container for extended periods to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.