Description

[(Triethylsilyl)Oxy]Methyl]-Pyrrolidine is a high-value organosilicon-protected pyrrolidine derivative, serving as a critical chiral building block and protecting group reagent in advanced organic synthesis. Its core value lies in enabling complex, multi-step synthetic routes with high selectivity and yield, which is essential for producing high-purity intermediates. This compound is primarily needed by research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key chiral synthon in the synthesis of complex drug candidates, particularly for nitrogen-containing heterocycles.
• Asymmetric Synthesis: Used as a chiral auxiliary or ligand precursor in catalytic asymmetric reactions to induce stereoselectivity.
• Amino Acid & Peptide Chemistry: Employed for the protection of amine functionalities during peptide coupling and modification sequences.
• Natural Product Synthesis: Building block for constructing pyrrolidine-based alkaloids and other natural product scaffolds.
• Agrochemical Research: Intermediate in the development of novel herbicides, fungicides, and insecticides with specific stereochemistry.
• Material Science: Precursor for functionalized polymers or surface-modifying agents requiring specific organic-silicon linkages.

Basic Information

Product Name	[(Triethylsilyl)Oxy]Methyl]-Pyrrolidine
CAS No.	1402544-73-3
Molecular Formula	C12H27NOSi
Molecular Weight	229.44 g/mol
Synonyms	1-[[(Triethylsilyl)oxy]methyl]pyrrolidine; N-[[(Triethylsilyl)oxy]methyl]pyrrolidine; (Triethylsilyloxymethyl)pyrrolidine; Pyrrolidine, 1-[[(triethylsilyl)oxy]methyl]-; TES-protected pyrrolidinyl methanol; (Pyrrolidin-1-yl)methanol triethylsilyl ether; 1-(Triethylsilyloxymethyl)pyrrolidine
EINECS	Contact for details

Quality Control

Our [(Triethylsilyl)Oxy]Methyl]-Pyrrolidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and chiral purity analysis, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (if applicable)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.