Description

1-(3-Fluorophenyl)-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Pyrazole is a high-purity boronic ester derivative, a critical building block in modern synthetic chemistry. Its value lies in enabling efficient cross-coupling reactions, which are fundamental for constructing complex molecular architectures. This advanced intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries, where it is used to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Material Science Research: Serves as a monomer or functional unit in the creation of organic electronic materials, such as OLEDs and semiconductors.
• Chemical Biology & Proteomics: Employed as a versatile handle for bioconjugation and the development of chemical probes and inhibitors.
• Academic & R&D Laboratories: A valuable reagent for methodological development in organic synthesis and catalysis studies.
• Custom Synthesis & Contract Manufacturing: A critical starting material for the production of complex, bespoke organic molecules on a commercial scale.

Basic Information

Product Name	1-(3-Fluorophenyl)-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Pyrazole
CAS No.	1402240-90-7
Molecular Formula	C15H20BFN2O2
Molecular Weight	290.15 g/mol
Synonyms	3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-(3-fluorophenyl)-1H-pyrazole; 1-(3-Fluorophenyl)-3-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole; 1-(3-Fluorophenyl)pyrazole-3-boronic acid pinacol ester; 3-Borono-1-(3-fluorophenyl)-1H-pyrazole pinacol ester; 1-(3-Fluorophenyl)-1H-pyrazole-3-boronic acid pinacol ester; 1402240-90-7; 3-(Pinacolatoboryl)-1-(3-fluorophenyl)-1H-pyrazole
EINECS	Contact for details

Quality Control

Our 1-(3-Fluorophenyl)-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Pyrazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results. Our commitment to quality supports compliance with cGMP and ICH guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.