Description

3-Bromo-2-Methoxy-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine is a high-purity, advanced pharmaceutical intermediate and versatile building block for organic synthesis. This compound is critical for facilitating efficient cross-coupling reactions, enabling the rapid construction of complex molecular architectures. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for drug discovery and fine chemical manufacturing.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key boronic ester precursor for constructing biaryl and heterobiaryl systems prevalent in active pharmaceutical ingredients (APIs).
• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of potential drug candidates, especially kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides with complex pyridine-based structures.
• Material Science & OLED Development: Employed in the synthesis of organic semiconductors, ligands for catalysts, and emissive materials for electronic devices.
• Chemical Biology & Probe Development: Facilitates the creation of labeled compounds and molecular probes for biochemical and diagnostic applications.
• Custom Synthesis & Contract Manufacturing: An essential starting material for custom synthesis projects requiring functionalized pyridine cores.

Basic Information

Item	Details
Product Name	3-Bromo-2-Methoxy-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine
CAS No.	1402227-31-9
Molecular Formula	C12H17BBrNO3
Molecular Weight	314.00 g/mol
Synonyms	3-Bromo-2-methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 2-Methoxy-3-bromo-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3-bromo-2-methoxypyridine; 3-Bromo-2-methoxypyridine-4-boronic acid pinacol ester; Pyridine, 3-bromo-2-methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; (3-Bromo-2-methoxypyridin-4-yl)boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 3-Bromo-2-Methoxy-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) with detailed specifications are provided and available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and easily oxidized; for long-term storage, it is recommended to keep the container under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.