Description

5-Methyl-n-Boc-Imidazole-4-Boronic Acid Pinacol Ester CAS NO 1402174-59-7 is a high-value, protected boronic ester derivative, a crucial building block in modern synthetic organic chemistry. Its primary value lies in enabling the precise construction of complex molecules through palladium-catalyzed cross-coupling reactions, such as the Suzuki-Miyaura reaction. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to synthesize novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in the development of kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, enabling the introduction of the imidazole moiety.
• Material Science Research: Serves as a precursor for creating functionalized polymers and organic electronic materials.
• Chemical Biology Probes: Employed in the development of molecular probes and tools for studying biological processes.
• Cross-Coupling Reactions: Specifically designed for use in Suzuki-Miyaura couplings to form carbon-carbon bonds with high fidelity and efficiency.
• Library Synthesis: A valuable reagent for generating diverse compound libraries in medicinal chemistry for high-throughput screening.

Basic Information

Product Name	5-Methyl-n-Boc-Imidazole-4-Boronic Acid Pinacol Ester
CAS No.	1402174-59-7
Molecular Formula	C16H27BN2O4
Molecular Weight	322.21 g/mol
Synonyms	1-(tert-Butoxycarbonyl)-5-methyl-1H-imidazole-4-boronic acid pinacol ester; 5-Methyl-1-Boc-imidazole-4-boronic acid pinacol ester; 1-Boc-5-methylimidazole-4-boronic acid pinacol ester; tert-Butyl 5-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-imidazole-1-carboxylate; 5-Methyl-1H-imidazole-4-boronic acid, 1-(1,1-dimethylethyl) ester, 4,4,5,5-tetramethyl-1,3,2-dioxaborolane ester; Boc-Protected 5-Methylimidazole-4-Boronate Pinacol Ester
EINECS	Contact for details

Quality Control

Our 5-Methyl-n-Boc-Imidazole-4-Boronic Acid Pinacol Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality management system is designed to meet the stringent requirements of pharmaceutical and fine chemical industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability and purity. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.