Description

4-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Pyrazol-1-Yl)Benzonitrile is a high-value, multi-functional boronic ester derivative, serving as a critical building block in modern synthetic chemistry. Its core value lies in enabling efficient cross-coupling reactions, which are fundamental for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries who require precise and reliable intermediates for advanced R&D and production.

Application

• Pharmaceutical Intermediate: Key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides requiring specific aryl-aryl linkages.
• Organic Light-Emitting Diodes (OLEDs): Acts as a building block for electron-transport materials and emissive layer components in display and lighting technologies.
• Ligand and Catalyst Development: Employed in the synthesis of novel bidentate ligands and organometallic catalysts for asymmetric synthesis.
• Polymer and Material Science: Facilitates the creation of conjugated polymers and advanced organic materials with tailored electronic properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and sensors for biological target identification and validation.

Basic Information

Product Name	4-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Pyrazol-1-Yl)Benzonitrile
CAS No.	1402166-72-6
Molecular Formula	C16H18BN3O2
Molecular Weight	295.15 g/mol
Synonyms	4-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)benzonitrile; 1-(4-Cyanophenyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole; 4-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazol-1-yl]benzonitrile; 4-(4-(Pinacolatoboryl)-1H-pyrazol-1-yl)benzonitrile; 4-(4-(Pinacolboranyl)-1H-pyrazol-1-yl)benzonitrile; 4-(4-Borono-1H-pyrazol-1-yl)benzonitrile pinacol ester; 1402166-72-6
EINECS	Contact for details

Quality Control

Our 4-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Pyrazol-1-Yl)Benzonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent performance for sensitive cross-coupling applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.