Description

1-(2-Cyanophenyl)Pyrazole-4-Boronic Acid, Pinacol Ester is a high-purity, advanced pharmaceutical intermediate and key building block in modern synthetic chemistry. This compound is critical for facilitating efficient cross-coupling reactions, enabling the rapid construction of complex molecular architectures. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for the synthesis of novel active ingredients and functional molecules.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a versatile boronic ester reagent for constructing biaryl and heterobiaryl systems central to drug discovery.
• Pharmaceutical Intermediate: A key precursor in the synthesis of potential active pharmaceutical ingredients (APIs) targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides.
• Material Science Research: Employed in the creation of organic electronic materials, such as OLED emitters and charge-transport molecules.
• Chemical Biology & Probe Development: Facilitates the synthesis of molecular probes and labeled compounds for biochemical assays.
• Library Synthesis for High-Throughput Screening: Enables the efficient parallel synthesis of diverse compound libraries.

Basic Information

Product Name	1-(2-Cyanophenyl)Pyrazole-4-Boronic Acid, Pinacol Ester
CAS No.	1402166-71-5
Molecular Formula	C16H18BN3O2
Molecular Weight	295.15 g/mol
Synonyms	1-(2-Cyanophenyl)-1H-pyrazole-4-boronic acid pinacol ester; 2-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)benzonitrile; 1-(2-Cyanophenyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole; 1-(2-Cyanophenyl)pyrazole-4-boronic acid pinacol ester; 1-(2-Cyanophenyl)-1H-pyrazole-4-boronic acid, pinacol ester; Benzonitrile, 2-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]-
EINECS	Contact for details

Quality Control

Our 1-(2-Cyanophenyl)Pyrazole-4-Boronic Acid, Pinacol Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure high purity and consistent lot-to-lot performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided and available upon request to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.