Description

2-Cyclohexyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Thiazole is a high-value organoboron building block, specifically a thiazole-substituted boronic ester, essential for modern cross-coupling reactions. Its core value lies in enabling the precise and efficient construction of complex heterocyclic molecules, which are pivotal in advanced material and life science research. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for synthesizing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for the synthesis of novel drug candidates, particularly those containing the thiazole pharmacophore.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Material Science Research: Serves as a building block for creating organic electronic materials, such as OLED (Organic Light-Emitting Diode) emitters and charge transport materials.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and tags for studying biological processes and target engagement.
• Ligand & Catalyst Development: Acts as a precursor for synthesizing novel ligands and catalysts used in asymmetric synthesis and other catalytic transformations.
• Polymer & Resin Modification: Incorporated into polymer backbones to impart specific electronic or chemical properties for advanced polymeric materials.

Basic Information

Product Name	2-Cyclohexyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Thiazole
CAS No.	1402166-60-2
Molecular Formula	C15H24BNO2S
Molecular Weight	293.24 g/mol
Synonyms	2-Cyclohexyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3-thiazole; 2-Cyclohexyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiazole; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-cyclohexylthiazole; 2-Cyclohexylthiazole-5-boronic acid pinacol ester; Thiazole-5-boronic acid, 2-cyclohexyl-, pinacol ester; Pinacol 2-cyclohexylthiazole-5-boronate
EINECS	Contact for details

Quality Control

Our 2-Cyclohexyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Thiazole is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support our clients with custom synthesis and purity specifications tailored to specific project requirements, including options for analytical method development and validation support.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.